In the ongoing battle between cat-lovers and dog-lovers, dog people have a hefty weapon in their arsenal: a bizarre, mind-controlling parasite you can catch by cleaning your cat’s litterbox.
It’s true that this parasite exists, and it’s true that you can get it from your cat. But cat-lovers take heart — the truth is more complicated than the other half would have you think. And, yes, you can keep your cat.
Toxoplasma gondii — Toxo for short — is a tiny, single-celled parasite with a weird life history and a weirder host of consequences.
Cats get it by eating infected rodents. After being swallowed, the parasites invade the walls of the cat’s intestines, where they sexually reproduce, leaving behind millions of tiny cysts containing Toxo zygotes — these are called oocysts. Interestingly, cats (though all felines, not just house cats) are the only animal Toxo can use to sexually reproduce.
Later on, an infected cat will shed these oocytes in its feces — where, yes, you can then pick up the parasite from your cat’s litterbox. An infection with Toxo is called Toxoplasmosis, and once it’s in the body, it stays there. After an oocyst enters the body of a non-cat, it opens up and allows the Toxo zygotes to spill out, where they develop into a mobile, rapidly dividing life stage. Once they get into the blood stream, they are carried around to the body’s organs, including the brain.
Luckily, the human immune system is usually able to keep the parasites from getting out of hand. Pressure from the immune system forces them to cluster into little cysts in the brain and muscles. These cysts usually lie dormant, suppressed by the immune system. However, in the sick or the elderly, whose immune systems are weaker, the parasite can break free and cause serious illness, attacking organs — most notably the brain and eyes.
It’s also not exactly rare. The CDC reports that 22.5% of the US population over 12 has been infected with Toxo. In other parts of the world, the incidence of infection may be as high as 95%.
The most interesting thing about Toxo is what it does to an infected animal’s mind. Infected mice become more adventurous and less fearful of cats — in fact, they even seem to become drawn to cats. This sinister effect increases the rodent’s likelihood of being eaten and providing a chance for Toxo to enter the cat and reproduce.
Infected humans can be subject to some equally weird symptoms, which Kathleen Mcauliffe described in her extensive coverage for The Atlantic. Groundbreaking research showed that infected men tend to be more suspicious, withdrawn, and prone to breaking rules, while infected women are more trusting, outgoing, and law-abiding.
Both infected men and women are also more likely to be involved in traffic accidents, engage in self-violence, and — oddly — develop schizophrenia.
And for people with weakened immune systems, severe Toxoplasmosis infections can attack the eyes, brain, and other organs, and in extreme situations can result in death.
Pregnant women and the immunocompromised are the most at risk for adverse effects. Newly infected women, especially those infected during pregnancy, can pass the infection on to their child. This can result in severe consequences for the babies, such as damage to the eyes or nervous system.
The good news
But here are some facts to ease your minds, cat-owners.
First, cats only shed Toxo oocysts for three weeks after ingesting the parasite. That means indoor cats who aren’t running around gobbling up infected mice are basically safe. As for outdoor cats, The Atlantic writer Mcauliffe consulted Jaroslav Flegr, a Czech scientist who has devoted much of his career to the study of Toxoplasma gondii.
As for outdoor cats, they shed the parasite for only three weeks of their life, typically when they’re young and have just begun hunting. During that brief period, Flegr simply recommends taking care to keep kitchen counters and tables wiped clean.
Once they have shed the parasite, outdoor cats typically acquire immunity and will not become reinfected, meaning they will only shed the parasite once in their lives. So, to be honest, your beloved house cat is probably not controlling your mind after all.
Your food, on the other hand, is another story. While your pet kitty is almost certainly safe, some feral outdoor cat somewhere could still be infecting you — via the food you eat. Foodborne toxoplasmosis can help explain the high rate of infection in the United States and around the world.
The bad news
Infected cats can contaminate soil with their feces. The parasite stays viable in the wild for up to 18 months. The parasite can then be picked up by grazing animals — including food animals like pigs or cattle — or else it can rub off onto fruits and vegetables.
This means humans can contract the parasite by eating undercooked meat or unwashed veggies. In fact, the Centres for Disease Control and Prevention (CDC) consider Toxoplasmosis to be a leading cause of death by foodborne illness in the United States.
And it’s not just humans who are at risk. Toxoplasmosis in the California watershed poses a serious threat to sea otters, too.
It turns out cat feces can wash into waterways, which carry the Toxo parasites out into the sea. There, they can infect mussels, clams, and other shellfish that otters like to eat. Unfortunately, otters aren’t as good at fighting off the parasite as humans — once it has been ingested by the otters, it attacks their brains, causing lesions in the brain tissue and potentially death.
Since the late 90s, scientists have tracked toxoplasmosis infections in sea otters in California, and in the early 2000s it became apparent that Toxo was a major problem for California sea otters.
In 2006, the BBC reported that Toxo caused 17% of deaths in sea otters between 1998 and 2001. Other research has shown even higher infection rates. A 2005 study found that 52% of dead otters that washed up on the California coast between 1998 and 2004 were infected, and 38% of live ones had the parasite.
Scientists believe the problem is caused by cat feces washing into the California watershed. While both wild cats and feral domestic cats probably contribute to the problem, a 2013 study concluded that domestic cats were likely to have the biggest effect — despite generally having a lower parasite load than wild cats — because their populations are larger.
In general, for humans, thoroughly cooking your meat, washing your fruits and vegetables, and keeping surfaces in the house clean are a good protection against infection. And while Toxoplasmosis remains a strange and potentially scary presence in the world, it’s a pretty safe bet that you can go home and hug Fluffy tonight without too much anxiety.
NOW WATCH: Briefing videos
Business Insider Emails & Alerts
Site highlights each day to your inbox.