Rejection can feel genuinely devastating. But before you retreat into your tear-stained hovel to plot a new, anonymous life as a subsistence farmer in rural Australia (not that there’s anything wrong with that!), consider this: Some of the world’s most successful people have failed — sometimes more than once.
We’ve put together a list of indisputably successes, from movie stars to scientists, who experienced massive failure before they found fame and fortune.
Weaker people might have given up. Instead, these folks remained focused on their goals.
Scroll on to see the underdogs who went on to change the world.
Walt Disney was fired from the Kansas City Star because his editor felt he 'lacked imagination and had no good ideas.'
Oprah Winfrey was publicly fired from her first television job as an anchor in Baltimore for getting 'too emotionally invested in her stories.'
Steven Spielberg was rejected by the University of Southern California School of Cinematic Arts multiple times.
Honda was a mechanical genius who idolized Edison and rebelled against the norm. His passion for aggressive individualism was more fit for the United States, and he found himself alienated him from Japanese businessmen, who valued teamwork above all else. Honda then boldly challenged the American automotive industry in the 1970s and led a Japanese automotive revolution.
After having trouble adjusting to the culture and his classes, Dick Cheney dropped out of Yale -- and then returned, only to drop out for good.
Sir Isaac Newton's mother pulled him out of school as a boy so that he could run the family farm. He failed miserably.
Realising her son was not meant to till the land, she let Newton finish his basic education and was eventually persuaded to allow him to enroll in Cambridge University. Newton went on to become one of the greatest scientists of all time, revolutionising physics and mathematics.
Vera Wang failed to make the 1968 US Olympic figure-skating team. Then she became an editor at Vogue, but was passed over for the editor-in-chief position.
She began designing wedding gowns at age 40 and today is one of the premier designers in the fashion industry, with a business worth over $US1 billion. (She also found another way back into skating, designing costumes for skating champion Nancy Kerrigan.)
After that, things stayed bleak for a while, as Edison went onto be fired from his first two jobs, for not being suitably productive.
Edison went on to hold more than 1,000 patents and invented some world-changing devices, like the phonograph, practical electrical lamp, and a movie camera.
When Sidney Poitier first auditioned for the American Negro Theatre, he flubbed his lines and spoke in a heavy Caribbean accent, which made the director angrily tell him to stop wasting his time and go get a job as a dishwasher.
Poitier worked on his craft and eventually became a hugely successful Hollywood star. He won an Academy Award for Best Actor ('Lillies of the Field,' 1963) and helped break down the colour barrier in the American film industry.
In one of Fred Astaire's first screen tests, an executive wrote: 'Can't sing. Can't act. Slightly balding. Can dance a little.'
J.K. Rowling was a single mum living off welfare when she began writing the first 'Harry Potter' novel.
Charles Darwin was considered an average student. He gave up on a career in medicine and was going to school to become a parson.
Vincent Van Gogh sold only one painting, 'The Red Vineyard,' in his life, and the sale was just months before his death.
After Harrison Ford's first small movie role, an executive took him into his office and told him he'd never succeed in the movie business.
Theodor Seuss Geisel, better known as Dr. Seuss, had his first book rejected by 27 different publishers.
Lucille Ball appeared in so many second-tier films at the start of her career that she became known as 'The Queen of B Movies.'
Winston Churchill was estranged from his political party over ideological disagreements during the 'wilderness years' of 1929 to 1939.
However, after conducting a search, he was finally able to find a partner who had faith in him. Ford proved he had learned from his mistakes when Ford Motor Company forever changed the automotive industry and culture with his assembly line mode of production.
While developing his vacuum, Sir James Dyson went through 5,126 failed prototypes and his savings over 15 years.
Stephen King grew so frustrated over his attempt to write the novel 'Carrie' that he threw away the entire early draft.
Carey Mulligan was rejected from every single drama school she applied to. An auditor at Drama Center London told her to be a 'children's TV show presenter' instead.
'They were like, 'Go home! Or at least experience something other than boarding school,'' she recalls. She did, and has since gone onto starring roles on Broadway ('Skylight,' 'The Seagull') and in Hollywood ('An Education,' 'Shame').
A newly graduated English major, Gross did what many of us do: she took a teaching job in Buffalo's toughest inner city junior high. 'I couldn't keep the students in the classroom, I couldn't teach them a lesson, I couldn't do anything,' she told Marc Maron onstage at Brooklyn Academy of Music. Her tenure lasted all of six weeks.
Gross then discovered radio, and her long-running interview show, 'Fresh Air' now reaches more than 5 million listeners on 450 stations.
Saul Bellow's college English professor, the famed Norman Maclean, said he showed no signs of literary greatness and ultimately dismissed him as 'a dud.'
Bellow -- who went onto write masterworks like 'The Adventures of Augie March' and 'Humboldt's Gift' -- ultimately won the Pulitzer Prize, the Nobel Prize for Literature, a Guggenheim, and the National Medal of Arts. He is also the only writer to win the National Book Award for Fiction three separate times, and received the National Book Foundation's Medal for Distinguished Contribution to American Letters.
Lady Gaga got dropped by her record label, Island Def Jam, after 3 months. Upon receiving the news, she 'cried so hard she couldn't talk.'
Ang Lee failed Taiwan's college entrance exams -- twice. Then he tried to go to acting school, but his English wasn't good enough.
'I was always in shame that I could not focus on books,' Lee told ABC News. 'And I failed the college examinations. My father was my high school principle...That was bad.' In theatre school, he fell in love with the stage, but his English wasn't good enough.
Now, he's an a three-time Academy Award-winning director, and the man behind mega hits like 'Crouching Tiger Hidden Dragon,' 'Life of Pi,' and 'Brokeback Mountain.'
Growing up in the Marcy Projects in Brooklyn, Jay-Z worked to perfect his flow, his lyrics, and his references. When he couldn't get a single bite on his first CD, he and his friends sold the record 'out of the boot of their car next to Grey's Papaya.'
Now, the musician -- who's also an investor and entrepreneur -- is worth $US550 million, according to Forbes.