Here’s what’s been happening on Wall Street overnight

Krisztian Bocsi/ Bloomberg/ Getty Images

Welcome to Finance Insider, Business Insider’s summary of the top stories of the past 24 hours. Sign up here to get the best of Business Insider delivered direct to your inbox.

Stocks started Wednesday weaker for a second straight day, with tech companies once again among the biggest losers in the market.

The most notable tech mover has been Twitter, which reversed premarket gains and fell by as much as 6% on Wednesday even after topping analyst expectations while reporting its second quarterly profit in company history. Snap fell sharply, meanwhile, after the company confirmed it was testing a rollback of part of its Snapchat app redesign.

Elsewhere in markets news:

In deal news, Takeda has reached a deal to buy Adderall drugmaker Shire for $US64.3 billion. The two companies each have a phalanx of investment bankers advising on the proposed transaction, with four of the big five Wall Street banks landing a role.

NBC owner Comcast has gate-crashed Fox’s takeover of Sky with a £22 billion bid. The deal pits some of the sharpest minds in global mergers and acquisitions against each other, with the three sides represented by some of the biggest names on Wall Street and in the City of London.

And Salesforce is facing a “new competitive reality” in M&A and Microsoft has an important edge, according to Barclays.

Business Insider Emails & Alerts

Site highlights each day to your inbox.

Follow Business Insider Australia on Facebook, Twitter, LinkedIn, and Instagram.