Here's why nerve agents are some of the most deadly human-made chemicals on Earth

Chemical weapons like sarin and VX are known to kill men, women, and children with gruesome efficiency.

While their names differ, both are members of a larger group of human-made substances, called nerve agents, that all target the same system in the body.

The five most common and important nerve agents are tabun, sarin, soman, GF, and VX, according to the Organisation for the Prohibition of Chemical Weapons. In pure form, each is a colorless and mostly odourless liquid.

Any nerve agent can affect a person through the skin, breathing, ingestion, or all three routes, depending on the substance and how it’s used. For example, VX resembles a thick oil but dissolves in water (a drop was enough to kill Kim Jong Un’s brother), while sarin (which was spread over a Syria’s Idlib province on April 4) quickly evaporates into the air.

Special bombs can weaponize these liquids by rapidly dispersing them into a breathable form.

These two graphics illustrate what nerve agents do to the body and the biochemistry of how they work.

The way nerve agents attack the body’s cholinergic system produces these and other symptoms.

Specifically, the chemicals target an enzyme that drifts in the spaces, or synapses, between nerve cells and muscle cells.

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