The medical drama “Grey’s Anatomy” has kept viewers hooked since 2005. Now in its 15th season, the ABC series has had quite a few cast members come and go.
Some of the original cast have stayed on the show while others have left to pursue other ventures and projects.
Here’s what the original cast of “Grey’s Anatomy” is up to now.
Ellen Pompeo has made the iconic role of Meredith Grey her own.
The namesake of the show, Pompeo has played lead role Meredith Grey since episode one of the series.
Ellen Pompeo is the highest-paid television actress today.
While Grey went on to marry her “McDreamy” and have three children with him, Pompeo found love in her personal life as well with husband Chris Ivery. Like Grey, she started her own family during the show’s run. Pompeo remains the lead of the show, carrying the drama in its 15th year.
Sandra Oh was a fan-favourite for 10 seasons.
The Canadian actress played razor-sharp surgeon Cristina Yang for 10 seasons, departing the show in 2014.
Sandra Oh went from cardiothoracic surgery to “Killing Eve.”
Oh was nominated for an Emmy for best lead actress in a drama series on “Killing Eve” in 2018 for her portrayal of the titular character Eve Polastri. Oh was the first Asian woman to get a nomination in this category.
Patrick Dempsey broke fans’ hearts when he left the show in 2015.
Dempsey portrayed Derek Shepherd, the chief of neurosurgery, for 11 seasons on “Grey’s Anatomy.” He left the show in 2015 and told People magazine both he and show creator Shonda Rhimes agreed it was his time to go.
“I’m very grateful for ‘Grey’s Anatomy,’” Dempsey told People. “It’s given me the opportunity to do everything. But at the same time, there was a cost.”
And by cost, he meant the gruelling filming schedule that kept him from his wife and three children.
Patrick Dempsey has starred in a few shows and movies since.
Since starring as Derek Shepherd, Dempsey has appeared in the rom-com, “Bridget Jones’s Baby ” and the TV series “Devils.”
Katherine Heigl won an Emmy for her work on “Grey’s.”
Heigl won hearts early on in “Grey’s” as loveable and fierce Izzie Stevens, a surgeon who used to be a model. Heigl was nominated for a supporting actress in a drama series Emmy for her work on “Grey’s Anatomy” in 2007 and won.
Katherine Heigl left “Grey’s Anatomy” and went to act in other shows.
The year after her Emmy win, Heigl removed herself from Emmy consideration, allegedly angering creatives behind “Grey’s Anatomy.” Heigl left the show in 2010.
“Everyone had been working really hard to find an amicable and gracious way of letting go and moving on,” Heigl told Entertainment Weekly. “It’s sad but it’s what I wanted.”
The actress is married to Josh Kelley and they have three children together. Heigl joined “Suits” in 2018 after Meghan Markle’s royal departure.
T.R. Knight was a loveable favourite as George O’Malley.
Another initial series regular, T.R. Knight played the friendly and able doctor George O’Malley. But he left in season five due to reported issues with the creative direction of his character.
“My five-year experience proved to me that I could not trust any answer that was given,” Knight told CNN. “And with respect, I’m going to leave it at that.”
T.R. Knight has since gotten married and starred in other projects.
He has since been in “The Good Wife,” “The Catch,” and “Genius,” among other projects.
Justin Chambers plays rough-around-the-edges Alex Karev.
Another one of the original intern group, Justin Chambers played pediatric surgeon Alex Karev.
Justin Chambers is one of the few original cast members who’s still on the show.
He is one of the few to remain on the show for its currently 15-season run. Chambers is married to Keisha Chambers and they have five children.
And, his on-screen character Karev has also since gotten married to Jo Wilson.
Chandra Wilson plays tough Miranda Bailey, the teacher from the start.
Wilson plays the loveable and tough Miranda Bailey, who was the core group of interns’ resident back in the beginning of the show’s run.
Chandra Wilson still has a lead role on “Grey’s.”
Wilson was nominated for a best supporting actress in a drama series Emmy for her role as Miranda Bailey in 2006, 2007, 2008, and 2009. Wilson has also appeared on “General Hospital.”
James Pickens Jr. will always be the “Chief” in many fans’ hearts.
Pickens Jr. plays the role of Richard Webber, a Grey-Sloan Memorial veteran who was romantically involved with Meredith Grey’s mother, Ellis, and is now married to Jackson Avery’s mother, Catherine.
James Pickens Jr. is still on “Grey’s Anatomy.”
Pickens Jr. is still currently on “Grey’s” and appeared in season 10 of “Roseanne.”
Kate Walsh joined the series at the end of season one.
Walsh showed up at the end of the first season of “Grey’s Anatomy” as OB-GYN Addison Montgomery, Derek Shepherd’s estranged wife. Her role initially in the show was to serve as part of the love triangle between herself, Derek, and Grey.
Kate Walsh got a spin-off and has since acted in other series.
After a few seasons of “Grey’s,” Addison became such a show favourite that Walsh earned the spin-off medical drama “Private Practice.”
Walsh left “Grey’s Anatomy” for good in season three and “Private Practice” lasted for six seasons, from 2007 to 2013.
Walsh has since acted in other projects, most recently in Netflix’s teen drama “13 Reasons Why.”
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