The vote capped a stunning clash between Speaker Nancy Pelosi and moderate Democrats that Rep. Ilhan Omar told reporters was a "shit show."
The spending plan includes funding for roads, bridges, and broadband. Expect engineering, construction, and machinery stocks to win out, BofA said.
Some moderate Democrats are threatening to block the plan until Biden infrastructure bill becomes law. Ocasio-Cortez blasted them as "conservative."
The Democrats' package doesn't include an extension of pandemic unemployment benefits for jobless Americans, which are set to end in a month.
Republicans and Democrats clashing over rival amendments to collect unpaid taxes on cryptocurrencies, which could stymie final passage.
Late in the talks, senators removed a measure to generate funds by cutting unemployment fraud. It could have kicked people off by mistake.
Manchin supports advancing a Democratic-only approach to infrastructure, but hasn't decided whether to support the hefty price tag.